Article
Multiplexed SNP genotyping using primer single-base extension (SBE) and microsphere arrays.
Current protocols in cytometry - 1 Nov 2005
Deshpande Alina, Valdez Yolanda, Nolan John P
Abstract excerpt
Single-nucleotide polymorphisms (SNPs), genome sites with single-base sequence differences between individual chromosomes, are the most common type of genetic variation. Single-base changes can result in disease phenotypes, confer susceptibility or resistance to toxins or pathogens, or serve as markers for distinct allelic segments of DNA, making SNPs an important emerging tool in both basic and clinical...
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