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Article

A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension.

Genome research - 1 Apr 2000

Chen J, Iannone M A, Li M S, Taylor J D, Rivers P, Nelsen A J, Slentz-Kesler K A, Roses A, Weiner M P

Abstract excerpt

A rapid, high throughput readout for single-nucleotide polymorphism (SNP) analysis was developed employing single base chain extension and cytometric analysis of an array of fluorescent microspheres. An array of fluorescent microspheres was coupled with uniquely identifying sequences, termed complementary ZipCodes (cZipCodes), which allowed for multiplexing possibilities. For a given assay, querying a polymorphic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10779497
DOI: 10.1101/gr.10.4.549
PMCID: PMC310857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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