Article
Multiplexed SNP genotyping using nanobarcode particle technology.
Analytical and bioanalytical chemistry - 1 Feb 2006
Sha Michael Y, Walton Ian D, Norton Scott M, Taylor Micah, Yamanaka Mark, Natan Michael J, Xu Chongjun, Drmanac Snezana, Huang Steve, Borcherding Adam, Drmanac Radoje, Penn Sharron G
Abstract excerpt
Single-nucleotide polymorphisms (SNP) are the most common form of sequence variation in the human genome. Large-scale studies demand high-throughput SNP genotyping platforms. Here we demonstrate the potential of encoded nanowires for use in a particles-based universal array for high-throughput SNP genotyping. The particles are encoded sub-micron metallic nanorods manufactured by electroplating inert metals such...
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