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Article

Flow cytometry-based minisequencing: a new platform for high-throughput single-nucleotide polymorphism scoring.

Genomics - 1 Jun 2000

Cai H, White P S, Torney D, Deshpande A, Wang Z, Keller R A, Marrone B, Nolan J P

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) are the most abundant type of human genetic variation. These variable sites are present at high density in the genome, making them powerful tools for mapping and diagnosing disease-related alleles. We have developed a sensitive and rapid flow cytometry-based assay for the multiplexed analysis of SNPs based on polymerase-mediated primer extension, or minisequencing, using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10860658
DOI: 10.1006/geno.2000.6218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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