Article
Suspension arrays for high throughput, multiplexed single nucleotide polymorphism genotyping.
Cytometry - 1 Jun 2000
Armstrong B, Stewart M, Mazumder A
Abstract excerpt
BACKGROUND: Genetic diversity can help explain disease susceptibility and differential drug response. The most common type of variant is the single nucleotide polymorphism (SNP). We present a low-cost, high throughput assay for SNP genotyping. METHODS: The assay uses oligonucleotide probes covalently attached to fluorescently encoded microspheres. These probes are hybridized directly to fluorescently labeled...
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