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Article

Loss of heterozygosity of chromosome 8p and 11p in the dysplastic nodule and hepatocellular carcinoma.

Journal of gastroenterology and hepatology - 1 Apr 2003

Kahng Yoon Seob, Lee Youn Soo, Kim Byung Kee, Park Won Sang, Lee Jung Yong, Kang Chang Suk

Abstract excerpt

BACKGROUND AND AIM: In hepatocarcinogenesis, both de novo and multistep pathways have been suggested, and in the latter a dysplastic nodule is the proposed precancerous lesion. But genetic changes involved in the dysplastic nodule are not well understood. In this study, we tried to determine whether allelic loss of the chromosome 8p and/or 11p could be involved in the development of the dysplastic nodule and/or...

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Source

Identifiers

PMID: 12653892
DOI: 10.1046/j.1440-1746.2003.02997.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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