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Article

Genomic assessments of the frequent loss of heterozygosity region on 8p21.3-p22 in head and neck squamous cell carcinoma.

Cancer genetics and cytogenetics - 15 Jul 2007

Ye Hui, Pungpravat Nisa, Huang Bau-Lin, Muzio Lorenzo L, Mariggiò Maria A, Chen Zugen, Wong David T, Zhou Xiaofeng

Abstract excerpt

Most human cancers are characterized by genetic instabilities. Chromosomal aberrations include segments of allelic imbalance identifiable by loss of heterozygosity (LOH) at polymorphic loci, which may be used to implicate regions harboring tumor suppressor genes. Here we performed whole-genome LOH profiling on 41 human head and neck squamous cell carcinoma (HNSCC) cell lines. Several frequent LOH regions were...

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Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 8

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Share to Head and Neck Neoplasms

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Source

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Identifiers

PMID: 17656251
DOI: 10.1016/j.cancergencyto.2007.04.003
PMCID: PMC2000851

Genes

MTUS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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