Article
Loss of heterozygosity at D8S262: an early genetic event of hepatocarcinogenesis.
Diagnostic pathology - 16 Jun 2015
Zhu Qiao, Gong Li, Liu Xiaoyan, Wang Jun, Ren Pin, Zhang Wendong, Yao Li, Han Xiujuan, Zhu Shaojun, Lan Miao, Li Yanhong, Zhang Wei
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) is a multi-factor, multi-step, multi-gene and complicated process resulting from the accumulation of sequential genetic and epigenetic alterations. An important change among them is from precancerous lesions to HCC. However, only few studies have been reported about the sequential genetic changes during hepatocarcinogenesis. METHODS: We observed firstly molecular...
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