Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer.

Cancer research - 1 Oct 1992

Emi M, Fujiwara Y, Nakajima T, Tsuchiya E, Tsuda H, Hirohashi S, Maeda Y, Tsuruta K, Miyaki M, Nakamura Y

Abstract excerpt

Frequent loss of heterozygosity at chromosomal loci in a specific tumor type may indicate the presence of a tumor suppressor gene. We have examined loss of heterozygosity on chromosome 8p in paired tumor and constitutional DNA from 346 patients representing seven different types of human cancer. Frequent allelic losses were observed in hepatocellular carcinoma (22 of 46 cases, 47.8%), in colorectal cancer (12 of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Deletion

Share to Genes, Tumor Suppressor

Share to Heterozygote

Share to Lung Neoplasms

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1356616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent loss of heterozygosity for loci on chromosome 8p in hepatocellular carcinoma, colorectal cancer, and lung cancer.PMID 1356616Read ↗

Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma.Semantic proximity Read ↗

Allelic loss at chromosome band 8p21.3‐p22 is associated with progression of hepatocellular carcinomaSemantic proximity Read ↗

Comprehensive allelotyping of human hepatocellular carcinoma.Semantic proximity Read ↗

Deletion mapping reveals two regions of chromosome 8 allele loss in colorectal carcinomas.Semantic proximity Read ↗

Loss of heterozygosity from the short arm of chromosome 8 is an early event in breast cancersSemantic proximity Read ↗

Loss of Heterozygosity Analysis and DNA Copy Number Measurement on 8p in Bladder Cancer Reveals Two Mechanisms of Allelic LossSemantic proximity Read ↗

Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular CarcinomaSemantic proximity Read ↗

Loss of heterozygosity of chromosome 8p and 11p in the dysplastic nodule and hepatocellular carcinoma.Semantic proximity Read ↗

High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation.Semantic proximity Read ↗

Genome-wide semiquantitative microsatellite analysis of human hepatocellular carcinoma: discrete mapping of smallest region of overlap of recurrent chromosomal gains and losses.Semantic proximity Read ↗

Frequent multiplication of the long arm of chromosome 8 in hepatocellular carcinoma.Semantic proximity Read ↗

Genomic assessments of the frequent loss of heterozygosity region on 8p21.3-p22 in head and neck squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.