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Article

PTEN/MMAC1 gene mutation is a rare event in soft tissue sarcomas without specific balanced translocations.

International journal of cancer - 20 Mar 2003

Saito Tsuyoshi, Oda Yoshinao, Kawaguchi Ken-ichi, Takahira Tomonari, Yamamoto Hidetaka, Tamiya Sadafumi, Tanaka Kazuhiro, Matsuda Shuichi, Sakamoto Akio, Iwamoto Yukihide, Tsuneyoshi Masazumi

Abstract excerpt

The tumor suppressor gene PTEN/MMAC1 was identified on chromosome 10q23.3, which is homozygously deleted in many human malignancies. The loss of chromosome 10q was also frequently reported in some types of soft tissue sarcomas. Our study was designed to investigate the frequency of PTEN/MMAC1 gene mutation and to evaluate the role of the PTEN/MMAC1 gene in the tumorigenesis of soft tissue sarcomas without...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12569572
DOI: 10.1002/ijc.10918

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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