Article
Investigation of MMAC/PTEN gene mutations and protein expression in low grade gliomas.
Cellular and molecular neurobiology - 1 Jul 2009
Cecener Gulsah, Tunca Berrin, Egeli Unal, Bekar Ahmet, Guler Gulnur, Vatan Ozgur, Tolunay Sahsine
Abstract excerpt
The MMAC/PTEN tumor suppressor gene has an essential biological role in the formation of glioblastomas. It is known that there are variations in genetic alterations in tumors that develop in patients with different ethnic backgrounds; thus, we aimed to evaluate the incidence of MMAC/PTEN mutations and protein expression among various low grade gliomas of Turkish patients. We investigated 28 low grade gliomas for...
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