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Article

PTEN/MMAC1 mutations in endometrial cancers.

Cancer research - 1 Nov 1997

Risinger J I, Hayes A K, Berchuck A, Barrett J C

Abstract excerpt

Endometrial carcinomas represent the most common gynecological cancer in the United States, yet the molecular genetic events that underlie the development of these tumors remain obscure. Chromosome 10 is implicated in the pathogenesis of endometrial carcinoma based on loss of heterozygosity (LOH)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9354433

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9354433-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

PTEN/MMAC1 mutations in endometrial cancers.PMID 9354433Read ↗

Somatic mutations of the PTEN/MMAC1 gene in fifteen Japanese endometrial cancers: evidence for inactivation of both alleles.Semantic proximity Read ↗

Mutation analysis of PTEN/MMAC1 in acute myeloid leukemiaSemantic proximity Read ↗

Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity.Semantic proximity Read ↗

Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors.Semantic proximity Read ↗

PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics.Semantic proximity Read ↗

Mutation analysis of PTEN/MMAC 1 in sporadic thyroid tumors.Semantic proximity Read ↗

PTEN mutations as predictive marker for the high-grade endometrial cancer development in slovak women.Semantic proximity Read ↗

Immunohistochemical analysis of PTEN in endometrial carcinoma: a tissue microarray study with a comparison of four commercial antibodies in correlation with molecular abnormalities.Semantic proximity Read ↗

Somatic mutations of the PTEN/NMAC1 gene associated with frequent chromosomal loss detected using comparative genomic hybridization in endometrial cancer.Semantic proximity Read ↗

Immunohistochemistry and Next-generation Sequencing Are Complementary Tests in Identifying PTEN Abnormality in Endometrial Carcinoma Biopsies.Semantic proximity Read ↗

Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.Semantic proximity Read ↗

Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing.Semantic proximity Read ↗

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