Article
Mutation analysis of the PTEN/MMAC1 gene in cancers of the digestive tract.
European journal of cancer (Oxford, England : 1990) - 1 Apr 1999
Chang J G, Chen Y J, Perng L I, Wang N M, Kao M C, Yang T Y, Chang C P, Tsai C H
Abstract excerpt
The 10q23.3 gene PTEN (phosphatase and Tensin homologue deleted on chromosome 10) or MMAC1 (mutated in multiple advanced cancers 1) was recently reported to undergo frequent mutation, including mutations and deletions in multiple advanced cancers. This study showed that the aberrant transcripts of this gene are frequently found in cancers of the digestive tract, paired non-cancerous tissues and normal peripheral...
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