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Article

Genotypic and phenotypic characterization of a putative tumor susceptibility gene, GNMT, in liver cancer.

Cancer research - 1 Feb 2003

Tseng Tzu-Ling, Shih Yi-Ping, Huang Yu-Chuen, Wang Chung-Kwe, Chen Pao-Huei, Chang Jan-Gowth, Yeh Kun-Tu, Chen Yi-Ming Arthur, Buetow Kenneth H

Abstract excerpt

Glycine N-methyltransferase (GNMT), a multifunctional protein involved in the maintenance of the genetic stability, is often down-regulated in hepatocellular carcinoma (HCC). Using genotypic characterization of GNMT in hepatoma cell lines and in a Taiwanese population with a high incidence of liver cancer we have investigated the role of this gene in the progression of liver cancer. Six novel polymorphisms,...

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Share to Carcinoma, Hepatocellular
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis

Share to Liver Neoplasms

Share to Loss of Heterozygosity

Share to Methyltransferases

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Source

Identifiers

PMID: 12566309

Genes

GNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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