Article
Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals.
Drug metabolism and pharmacokinetics - 1 Jan 2009
Yamamoto Akiko, Nonen Shinpei, Fukuda Tsuyoshi, Yamazaki Hiroshi, Azuma Junichi
Abstract excerpt
In the present study, we identified 5 novel single nucleotide polymorphisms (SNPs) in the gene ofglycine N-acyltransferase (GlyAT) by resequencing the entire coding region and the exon-intron junctions from 95 Japanese individuals. The allelic frequencies of 5 novel SNPs were 0.016 for -695T>C, 0.021 for -260C>T, 0.005 for 290C>T, 0.005 for 19371G>A, and 0.005 for 21289G>A. Genetic variants of -979C>G and...
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