Article
Association between an insertion/deletion polymorphism within 3'UTR of SGSM3 and risk of hepatocellular carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014
Wang Chaoqun, Zhao Hua, Zhao Xiankun, Wan Jiao, Wang Dayong, Bi Wanli, Jiang Xinghong, Gao Yuzhen
Abstract excerpt
Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy, and multiple host genetic factors are believed to contribute to HCC development. The small G protein signaling modulator 3 (SGSM3) has been shown to be associated with small G protein coupled receptor signal transduction pathway, suggesting a potential role in HCC susceptibility. We carried out a case-control study in a Chinese...
Topics
- 3' Untranslated Regions
- Adult
- Alleles
- Base Pairing
- Base Sequence
- Carcinoma, Hepatocellular
- Case-Control Studies
- DNA Mutational Analysis
- Female
- Gene Deletion