Article
Polymorphisms in METTL3 gene and hepatoblastoma risk in Chinese children: A seven-center case-control study.
Gene - 20 Oct 2021
Chen Huitong, Duan Fei, Wang Mi, Zhu Jinhong, Zhang Jiao, Cheng Jiwen, Li Li, Li Suhong, Li Yong, Yang Zhonghua, Xia Huimin, Niu Huizhong, He Jing
Abstract excerpt
Hepatoblastoma is the most common malignant liver cancer in childhood, yet its etiology remains unclear. As an m6A methylation modifier, methyltransferase like 3 (METTL3) has an active methyltransferase domain that functionally participates in various tumor occurrence and development. However, little is known about how METTL3 polymorphisms affect the occurrence of hepatoblastoma. Here, we attempted to investigate...
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