Article
Haplotypes, loss of heterozygosity, and expression levels of glycine N-methyltransferase in prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2007
Huang Yu-Chuen, Lee Cheng-Ming, Chen Marcelo, Chung Ming-Yi, Chang Yen-Hwa, Huang William Ji-Shian, Ho Donald Ming-Tak, Pan Chin-Chen, Wu Tony T, Yang Stone, Lin Ming-Wei, Hsieh Jer-Tsong, Chen Yi-Ming Arthur
Abstract excerpt
PURPOSE: Glycine N-methyltransferase (GNMT) affects genetic stability by regulating DNA methylation and interacting with environmental carcinogens. In a previous study, we showed that GNMT acts as a susceptibility gene for hepatocellular carcinoma. Here, we report on our efforts to characterize t...
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