An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk.

doi:10.1158/0008-5472.CAN-12-0010

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk.

Cancer research - 1 Dec 2012

Zhu Zhansheng, Gao Xueren, He Yan, Zhao Hua, Yu Qiang, Jiang Deke, Zhang Pingzhao, Ma Xiaopin, Huang Huixing, Dong Dong, Wan Jiao, Gu Zhenyong, Jiang Xinghong, Yu Long, Gao Yuzhen

Abstract excerpt

The Prolyl hydroxylase 1 (EGLN2) is known to affect tumorigenesis by regulating the degradation of hypoxia-inducible factor. Polymorphisms in EGLN2 may facilitate cancer cell survival under hypoxic conditions and directly associate with cancer susceptibility. Here, we examined the contribution of a 4-bp insertion/deletion polymorphism (rs10680577) within the distal promoter of EGLN2 to the risk of hepatocelluar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Genetic Association Studies

Share to Hypoxia-Inducible Factor-Proline Dioxygenases

Share to Nuclear Proteins

Share to Procollagen-Proline Dioxygenase

Share to Promoter Regions, Genetic

Share to RNA, Long Noncoding

Source

Open in PubMed

Identifiers

PMID: 23026137
DOI: 10.1158/0008-5472.CAN-12-0010

Genes

EGLN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk.PMID 23026137Read ↗

Correlations of an Insertion/Deletion Polymorphism (rs10680577) in the RERT-lncRNA with the Susceptibility, Clinicopathological Features, and Prognosis of Lung Cancer.Semantic proximity Read ↗

An insertion/deletion polymorphism within the proximal promoter of EGLN2 is associated with susceptibility for gastric cancer in the Chinese population.Semantic proximity Read ↗

An enhancer variant at 16q22.1 predisposes to hepatocellular carcinoma via regulating PRMT7 expression.Semantic proximity Read ↗

Genetic Variants in EMT-Related lncRNAs Modulate the Risk of Colorectal Cancer in the Chinese Population.Semantic proximity Read ↗

Integrated functional genomics-identified LYRM4 promotes fumarate accumulation and hepatocellular carcinoma progression.Semantic proximity Read ↗

Genetic variations in nucleotide excision repair pathway genes and hepatoblastoma susceptibility.Semantic proximity Read ↗

An insertion/deletion polymorphism within the promoter of EGLN2 is associated with susceptibility to colorectal cancer.Semantic proximity Read ↗

Exonuclease 1 is a Potential Diagnostic and Prognostic Biomarker in Hepatocellular CarcinomaSemantic proximity Read ↗

NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors.Semantic proximity Read ↗

The DNA repair gene ERCC6 rs1917799 polymorphism is associated with gastric cancer risk in Chinese.Semantic proximity Read ↗

The Effect of SNPs in IncRNA as CeRNA on The Risk and Prognosis of Hepatocellular CarcinomaSemantic proximity Read ↗

Associations between the rs6010620 polymorphism in RTEL1 and risk of glioma: a meta-analysis of 20,711 participants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.