Article
Genetic and expression analysis of the KCNRG gene in hepatocellular carcinomas.
Experimental & molecular medicine - 30 Jun 2006
Cho Yong Gu, Kim Chang Jae, Song Jae Hwi, Rhie Duck Joo, Park Yong Kyu, Kim Su Young, Nam Suk Woo, Yoo Nam Jin, Lee Jung Young, Park Won Sang
Abstract excerpt
The potassium channels are ubiquitous multisubunit membrane proteins, and potassium-dependent alterations in the membrane potential play an important role in the proliferation of many types of cells. This study analyzed the mutation, allelic loss and expression patterns of the KCNRG gene in 77 HCCs in order to determine if the KCNRG gene, which encodes the potassium channel regulating protein, is involved in the...
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