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Article

Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease.

Neurology - 28 Jan 2003

Bennett D A, Wilson R S, Schneider J A, Evans D A, Aggarwal N T, Arnold S E, Cochran E J, Berry-Kravis E, Bienias J L

Abstract excerpt

OBJECTIVE: To test the hypothesis that the APOE epsilon4 allele is associated with the clinical manifestations of AD through an association with the pathologic hallmarks of disease. METHODS: Participants were older Catholic nuns, priests, and brothers who agreed to annual neurologic and neuropsychological evaluation for AD and other common neurologic conditions and brain autopsy at the time of death. There were...

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Source

Identifiers

PMID: 12552039
DOI: 10.1212/01.wnl.0000042478.08543.f7

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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