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Article

Apolipoprotein E epsilon4 allele increases risk for psychotic symptoms in Alzheimer's disease.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2007

Zdanys Kristina F, Kleiman Timothy G, MacAvoy Martha G, Black Benjamin T, Rightmer Tracy E, Grey Monique, Garman Katherine S, Tampi Rajesh R, Gelernter Joel, van Dyck Christopher H

Abstract excerpt

The apolipoprotein E (ApoE) epsilon4 allele is a well-documented genetic risk factor for sporadic Alzheimer's disease (AD). Its association with psychopathology among AD patients has been the subject of discrepant reports. We aimed to determine whether ApoE epsilon4+ and epsilon4- AD patients exhibit a different risk profile for psychotic symptoms and other behavioral disturbances. The Neuropsychiatric Inventory...

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PMID: 16841077
DOI: 10.1038/sj.npp.1301148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Apolipoprotein E epsilon4 allele increases risk for psychotic symptoms in Alzheimer's disease.PMID 16841077Read ↗

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