Article
Apolipoprotein E epsilon4 allele increases risk for psychotic symptoms in Alzheimer's disease.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2007
Zdanys Kristina F, Kleiman Timothy G, MacAvoy Martha G, Black Benjamin T, Rightmer Tracy E, Grey Monique, Garman Katherine S, Tampi Rajesh R, Gelernter Joel, van Dyck Christopher H
Abstract excerpt
The apolipoprotein E (ApoE) epsilon4 allele is a well-documented genetic risk factor for sporadic Alzheimer's disease (AD). Its association with psychopathology among AD patients has been the subject of discrepant reports. We aimed to determine whether ApoE epsilon4+ and epsilon4- AD patients exh...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoprotein E4
- Chi-Square Distribution
- Female
- Humans
- Logistic Models
- Male
- Neuropsychological Tests
- Psychotic Disorders
- Risk
- Statistics, Nonparametric