Article
The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons.
Neuroepidemiology - 1 Jan 2010
Boyle Patricia A, Buchman Aron S, Wilson Robert S, Kelly Jeremiah F, Bennett David A
Abstract excerpt
BACKGROUND: The apolipoprotein E (APOE) epsilon4 allele is a well-known risk factor for the development of Alzheimer's disease, but little is known about the association of the epsilon4 allele with incident mild cognitive impairment (MCI). OBJECTIVE: Test the hypothesis that the epsilon4 allele is associated with an increased risk of developing MCI. METHODS: More than 600 older Catholic clergy members from the...
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