Article
The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period.
Archives of neurology - 1 Jul 2002
Wilson Robert S, Schneider Julie A, Barnes Lisa L, Beckett Laurel A, Aggarwal Neelum T, Cochran Elizabeth J, Berry-Kravis Elizabeth, Bach Julie, Fox Jacob H, Evans Denis A, Bennett David A
Abstract excerpt
CONTEXT: Impairment of episodic memory is an early and defining feature of Alzheimer disease (AD). The apolipoprotein E (APOE) epsilon 4 allele is known to influence risk of AD but it has been difficult to establish whether it affects episodic memory differently from other cognitive functions. OBJECTIVE: To examine the association of epsilon 4 with decline in different cognitive systems. DESIGN: Longitudinal...
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