Article
Single-nucleotide polymorphism detection using peptide nucleic acids.
Expert review of molecular diagnostics - 1 Jan 2003
Igloi Gabor L
Abstract excerpt
Variations in the human DNA sequence between individuals can be an indication of predisposition to disease, affect the response to drug treatment, or more directly, be the fingerprint of an inheritable trait or defect. Significant efforts at improving the speed, accuracy and sensitivity of detecting such polymorphisms have led to the development of a number of powerful approaches. Sequence-specific base pairing...
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