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Article

SNPs detection by a single-strand specific nuclease on a PNA zip-code microarray.

Biosensors & bioelectronics - 15 Feb 2009

Mun Hyo Young, Girigoswami Agnishwar, Jung Cheulhee, Cho Dae-Yeon, Park Hyun Gyu

Abstract excerpt

In this report, a reliable peptide nucleic acid (PNA) microarray-based method for accurately detecting single nucleotide polymorphism (SNP) in human genes is described. The technique relies on the mismatched cleavage activity of a single-strand specific (SSS) nuclease. PCR amplification was performed to prepare gene fragments containing the mutation sites. The amplified fragments were then employed as templates...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18930386
DOI: 10.1016/j.bios.2008.08.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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