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Article

Novel analysis for single nucleotide polymorphism using cationic comb-type copolymers.

Nucleic acids symposium series (2004) - 1 Jan 2007

Shimada Naohiko, Muraki Kentaro, Anai Taro, Kano Arihiro, Maruyama Atsushi

Abstract excerpt

We have focused on the DNA strand exchange reaction (SER) as a format of a single-base mismatch detection. We employed a partially double-stranded (PDS) DNA probe having a single-stranded (ss) portion. We could rapidly recognize a single-base mismatch by the SER rates between the PDS probes and target ss DNAs. In the presence of cationic comb-type copolymers (PLL-g-Dex) and betaine, the PDS probes could clearly...

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PMID: 18029725
DOI: 10.1093/nass/nrm170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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