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Article

HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA105-DQB102 haplotype is carried.

Tissue antigens - 1 Aug 2002

Louka A S, Nilsson S, Olsson M, Talseth B, Lie B A, Ek J, Gudjónsdóttir A H, Ascher H, Sollid L M

Abstract excerpt

Predisposition to coeliac disease (CD) involves HLA genes. We investigated whether any haplotypes modify risk when carried trans to a known high-risk haplotype, DQA1*05-DQB1*02. Earlier attempts to rank levels of risk contributed by the 'other' haplotype were burdened by use of case-control populations; haplotype frequencies were estimated and homozygosity was only presumed. In contrast, exact haplotypes can be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12392509
DOI: 10.1034/j.1399-0039.2002.600205.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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