Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heritability of non-HLA genetics in coeliac disease: a population-based study in 107 000 twins.

Gut - 1 Nov 2016

Kuja-Halkola Ralf, Lebwohl Benjamin, Halfvarson Jonas, Wijmenga Cisca, Magnusson Patrik K E, Ludvigsson Jonas F

Abstract excerpt

BACKGROUND AND OBJECTIVE: Almost 100% individuals with coeliac disease (CD) are carriers of the human leucocyte antigen (HLA) DQ2/DQ8 alleles. Earlier studies have, however, failed to consider the HLA system when estimating heritability in CD, thus violating an underlying assumption of heritability analysis. We examined the heritability of CD in a large population-based sample of twins, considering HLA. DESIGN:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Celiac Disease
Share to HLA-DQ Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intestine, Small

Share to Multifactorial Inheritance

Share to Registries

Share to Sweden

Share to Twins, Dizygotic

Share to Twins, Monozygotic

Source

Identifiers

PMID: 27207974
DOI: 10.1136/gutjnl-2016-311713

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heritability of non-HLA genetics in coeliac disease: a population-based study in 107 000 twins.PMID 27207974Read ↗

Genetics of coeliac diseaseSemantic proximity Read ↗

The first large population based twin study of coeliac disease.Semantic proximity Read ↗

Concordance, disease progression, and heritability of coeliac disease in Italian twins.Semantic proximity Read ↗

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants.Semantic proximity Read ↗

Genetics in coeliac disease.Semantic proximity Read ↗

Phenome-wide association study in adult coeliac disease: role of HLA subtype.Semantic proximity Read ↗

Heritability in inflammatory bowel disease: from the first twin study to genome-wide association studies.Semantic proximity Read ↗

The genetics of celiac disease: A comprehensive review of clinical implications.Semantic proximity Read ↗

HLA related genetic risk for coeliac disease.Semantic proximity Read ↗

Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3Semantic proximity Read ↗

Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease.Semantic proximity Read ↗

Combination Testing Using a Single MSH5 Variant alongside HLA Haplotypes Improves the Sensitivity of Predicting Coeliac Disease Risk in the Polish Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.