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Article

Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative Splicing

21 Oct 2002

Abstract excerpt

Fission yeast Pot1 (protection of telomeres) is a single-stranded telomeric DNA binding protein with a critical role in ensuring chromosome stability. A putative human homolog (hPot1) was previously identified, based on moderate sequence similarity with fission yeast Pot1 and telomere end-binding proteins from ciliated protozoa. Using indirect immunofluorescence, we show here that epitope-tagged hPot1 localizes...

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Share to Advanced biosensing and bioanalysis techniques
Share to Chromosomal and Genetic Variations
Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 12391173
DOI: 10.1128/mcb.22.22.8079-8087.2002

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Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative SplicingPMID 12391173Read ↗

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