Article
Cut1/separase C-terminus affects spindle pole body positioning in interphase of fission yeast: pointed nuclear formation.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2002
Nakamura Takahiro, Nagao Koji, Nakaseko Yukinobu, Yanagida Mitsuhiro
Abstract excerpt
BACKGROUND: The separase-securin complex is required for anaphase. Separase activated by securin destruction cleaves the cohesin subunit Scc1/Rad21 enriched in kinetochores. Fission yeast Cut1/separase resides in interphase cytoplasm and mobilizes to the spindle and the spindle pole bodies (SPBs) in mitosis, while Cut2/securin remains in the nucleus from interphase to metaphase, and temporarily locates at the...
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