Article

Kinesin-5/Cut7 moves bidirectionally on fission-yeast spindles with activity that increases in anaphase

2022-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Kinesin-5 motors are essential to separate mitotic spindle poles and assemble a bipolar spindle in many organisms. These tetrameric motors crosslink and slide apart antiparallel microtubules via microtubule plus-end-directed motility. However, kinesin-5s typically accumulate more at spindle poles than in the center of the spindle where antiparallel microtubule overlaps are most numerous. While t...

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Literature Corpus work: 08c5451f-feb1-55c0-bf19-353d74dad085
DOI: 10.1101/2022.08.01.502387

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