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Article

The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.

Genes & development - 1 Apr 1998

Bridge A J, Morphew M, Bartlett R, Hagan I M

Abstract excerpt

During fission yeast mitosis, the duplicated spindle pole bodies (SPBs) nucleate microtubule arrays that interdigitate to form the mitotic spindle. cut12.1 mutants form a monopolar mitotic spindle, chromosome segregation fails, and the mutant undergoes a lethal cytokinesis. The cut12(+) gene encodes a novel 62-kD protein with two predicted coiled coil regions, and one consensus phosphorylation site for p34(cdc2)...

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Identifiers

PMID: 9531532
DOI: 10.1101/gad.12.7.927
PMCID: PMC316675

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The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.PMID 9531532Read ↗

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