Article

Two spatially distinct Kinesin-14 Pkl1 and Klp2 generate collaborative inward forces against Kinesin-5 Cut7 in <i>S. pombe</i>

2017-10-19

Abstract excerpt

<h4>ABSTRACT</h4> Kinesin motors play central roles in bipolar spindle assembly. In many eukaryotes, spindle pole separation is driven by Kinesin-5 that generates outward force. This outward force is balanced by antagonistic inward force elicited by Kinesin-14 and/or Dynein. In fission yeast, two Kinesin-14s, Pkl1 and Klp2, play an opposing role against Kinesin-5/Cut7. However, how these two Kinesin-14s coordinat...

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Literature Corpus work: 1745b5ed-2414-54fd-967b-40ed38124d4e
DOI: 10.1101/205815

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