Article
The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene.
Cell - 7 Sept 1990
Uzawa S, Samejima I, Hirano T, Tanaka K, Yanagida M
Abstract excerpt
Mutations in the fission yeast cut1+, cut2+, and cut10+ genes uncouple normally coordinated mitotic events and deregulate, rather than arrest, mitosis. DNA synthesis continues, making polyploid nuclei with several spindles. Multiple, aberrant spindle pole bodies (SPBs) are produced in cut1 mutant...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Genes, Fungal
- Kinetics
- Microscopy, Electron
- Mitosis
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
- Saccharomycetales
- Schizosaccharomyces
- Sequence Homology, Nucleic Acid
- Temperature