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Article

cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.

Molecular biology of the cell - 1 Oct 1998

West R R, Vaisberg E V, Ding R, Nurse P, McIntosh J R

Abstract excerpt

The "cut" mutants of Schizosaccharomyces pombe are defective in spindle formation and/or chromosome segregation, but they proceed through the cell cycle, resulting in lethality. Analysis of temperature-sensitive alleles of cut11(+) suggests that this gene is required for the formation of a functional bipolar spindle. Defective spindle structure was revealed with fluorescent probes for tubulin and DNA....

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Identifiers

PMID: 9763447
DOI: 10.1091/mbc.9.10.2839
PMCID: PMC25557

Genes

NDC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe.PMID 9763447Read ↗

Identification of seven new cut genes involved in Schizosaccharomyces pombe mitosis.Semantic proximity Read ↗

The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.Semantic proximity Read ↗

Kinesin-related cut7 protein associates with mitotic and meiotic spindles in fission yeast.Semantic proximity Read ↗

New mutations in the core Schizosaccharomyces pombe spindle pole body scaffold Ppc89 reveal separable functions in regulating cell division.Semantic proximity Read ↗

Suppression of the Schizosaccharomyces pombe cut12.1 cell-cycle defect by mutations in cdc25 and genes involved in transcriptional and translational control.Semantic proximity Read ↗

Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase.Semantic proximity Read ↗

The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene.Semantic proximity Read ↗

Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene.Semantic proximity Read ↗

The spindle pole bodies facilitate nuclear envelope division during closed mitosis in fission yeast.Semantic proximity Read ↗

The novel fission yeast protein Pal1p interacts with Hip1-related Sla2p/End4p and is involved in cellular morphogenesis.Semantic proximity Read ↗

Mutations affecting spindle pole body and mitotic exit network function are synthetically lethal with a deletion of the nucleoporin NUP1 in S. cerevisiae.Semantic proximity Read ↗

A screen for genes involved in the anaphase proteolytic pathway identifies tsm1(+), a novel Schizosaccharomyces pombe gene important for microtubule integrity.Semantic proximity Read ↗

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