Article
Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant mice.
Genes & development - 15 Oct 2002
Oster Henrik, Yasui Akira, van der Horst Gijsbertus T J, Albrecht Urs
Abstract excerpt
Many biochemical, physiological, and behavioral processes display daily rhythms generated by an internal timekeeping mechanism referred to as the circadian clock. The core oscillator driving this clock is located in the ventral part of the hypothalamus, the so called suprachiasmatic nuclei (SCN). At the molecular level, this oscillator is thought to be composed of interlocking autoregulatory feedback loops...
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