Article
Genetics and neurobiology of circadian clocks in mammals.
Cold Spring Harbor symposia on quantitative biology - 1 Jan 2007
Siepka Sandra M, Yoo Seung-Hee, Park Junghea, Lee Choogon, Takahashi Joseph S
Abstract excerpt
In animals, circadian behavior can be analyzed as an integrated system, beginning with genes and leading ultimately to behavioral outputs. In the last decade, the molecular mechanism of circadian clocks has been unraveled primarily by the use of phenotype-driven (forward) genetic analysis in a number of model systems. Circadian oscillations are generated by a set of genes forming a transcriptional autoregulatory...
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