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Article

Loss of heterozygosity and PCR artifacts in a microsatellite analysis of psoriasis and colorectal cancer.

Journal of Korean medical science - 1 Oct 2002

Hyun Jeong Sun, Jo Bo-Kyong, Park Chul Jong, Yi Jong Yuk, Lee Jun Young, Rhyu Mun-Gan

Abstract excerpt

Although a loss of heterozygosity (LOH) is commonly observed using microsatellite markers in a cell-proliferating malignant disorder, controversial findings of psoriasis, a keratinocyte-outgrowth disease, remain to be explained. It was hypothesized that unstable natures of the microsatellite markers for the polymerase chain reaction (PCR) might give a rise to either a false-positive or -negative LOH. Twenty-one...

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Identifiers

PMID: 12378016
DOI: 10.3346/jkms.2002.17.5.641
PMCID: PMC3054942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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