Allelic instability in the mitosis model and the inheritance of psoriasis.

doi:10.1016/0190-9622(95)90182-5

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Article

Allelic instability in the mitosis model and the inheritance of psoriasis.

Journal of the American Academy of Dermatology - 1 Jan 1995

Theeuwes M, Morhenn V

Abstract excerpt

BACKGROUND: Allelic instability in mitosis has been proposed as a model for dominantly inherited diseases. OBJECTIVE: Our purpose was to analyze our own and published data on the inheritance of psoriasis according to the predictions of the allelic instability-in-mitosis model. METHODS: Frequency of psoriasis in father, mother, and siblings was extracted or calculated from data in the literature. Our case records...

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