Article
Molecular genetic analysis of surveillance biopsy samples from Barrett's mucosa--significance of sampling.
Pathology, research and practice - 1 Jan 2008
Werther Meike, Saure Christoph, Pahl René, Schorr Friedrich, Rüschoff Josef, Alles Jens Uwe, Heinmöller Ernst
Abstract excerpt
Our aim was to determine the spectrum and accumulation of mutations in surveillance biopsies from Barrett's mucosa of individual patients during follow-up. We performed loss of heterozygosity (LOH) analysis of six recently described tumor suppressor genes relevant for the carcinogenesis of Barret...
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