Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of heterozygosity and microsatellite instability in human non-neoplastic hepatic lesions.

Liver - 1 Aug 1999

Tsopanomichalou M, Kouroumalis E, Ergazaki M, Spandidos D A

Abstract excerpt

AIMS/BACKGROUND: Carcinogenesis is thought to be a multistage process that occurs as a result of mutations in oncogenes and tumor suppressor genes. One way to monitor a vast range of these changes is by microsatellite PCR amplification that detects loss of heterozygosity and microsatellite instability between normal and tumor specimens of the same subject. Viral cirrhosis is considered a strong predisposing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-II
Share to Biopsy, Needle
Share to Chromosome Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 1

Share to Chromosomes, Human, Pair 17

Share to Chromosomes, Human, Pair 9

Share to Liver Diseases

Share to Loss of Heterozygosity

Source

Identifiers

PMID: 10459629
DOI: 10.1111/j.1478-3231.1999.tb00054.x

Genes

APOA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of heterozygosity and microsatellite instability in human non-neoplastic hepatic lesions.PMID 10459629Read ↗

Molecular diagnosis of primary liver cancer by microsatellite DNA analysis in the serum.Semantic proximity Read ↗

Loss of heterozygosity of chromosome 8p and 11p in the dysplastic nodule and hepatocellular carcinoma.Semantic proximity Read ↗

Microsatellite instability associated with hepatocarcinogenesis.Semantic proximity Read ↗

Genetic Instability and Aberrant Dna Methylation in Chronic Hepatitis and Cirrhosis—A Comprehensive Study of Loss of Heterozygosity and Microsatellite Instability At 39 Loci and Dna Hypermethylation on 8 Cpg Islands in Microdissected Specimens From Patients With Hepatocellular CarcinomaSemantic proximity Read ↗

Comprehensive allelotyping of human hepatocellular carcinoma.Semantic proximity Read ↗

Association of cumulative allelic losses with tumor aggressiveness in hepatocellular carcinoma.Semantic proximity Read ↗

The application of microsatellites in molecular pathology.Semantic proximity Read ↗

Quantitative evaluation of genomic instability as a possible predictor for development of hepatocellular carcinoma: Comparison of loss of heterozygosity and replication errorSemantic proximity Read ↗

Microsatellite instability and loss of heterozygosity at DNA mismatch repair gene loci occurs during hepatic carcinogenesisSemantic proximity Read ↗

Microsatellite instability and allelic imbalance in primary and secondary colorectal cancer.Semantic proximity Read ↗

Comparison of the Allelic Alterations between InDel and STR Markers in Tumoral Tissues Used for Forensic Purposes.Semantic proximity Read ↗

Relationship between loss of heterozygosity of tumor suppressor genes and histologic differentiation in hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.