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Article

Multiplex loss of heterozygosity analysis by using single or very few cells.

The Journal of molecular diagnostics : JMD - 1 Aug 2002

Cui Xiangfeng, Feiner Helen, Li Honghua

Abstract excerpt

Loss of heterozygosity (LOH) is an indication of tumor suppressor gene inactivation. However, loss of heterozygosity analysis has been limited to either a small scale or to very few genetic markers. To significantly increase the scale of study and to include a large number of markers in the analysis, experimental conditions were established for using single cells or single cell equivalent with 10 markers typed...

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Identifiers

PMID: 12169679
DOI: 10.1016/S1525-1578(10)60699-X
PMCID: PMC1906978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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