Article
High frequency of allelic loss in dysplastic lichenoid lesions.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 2000
Zhang L, Cheng X, Li Y, Poh C, Zeng T, Priddy R, Lovas J, Freedman P, Daley T, Rosin M P
Abstract excerpt
Oral lichen planus (OLP) is a common mucosal condition that is considered premalignant by some, whereas others argue that only lichenoid lesions with epithelial dysplasia are at risk of progressing into oral carcinoma. A recent study from this laboratory used microsatellite analysis to evaluate OLP for loss of heterozygosity (LOH) at loci on three chromosomal arms (3p, 9p, and 17p) (Am J Path...
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