Article
Spontaneous length variation in microsatellite DNA from human T-cell clones.
Genes, chromosomes & cancer - 1 Nov 1995
Hackman P, Gabbani G, Osterholm A M, Hellgren D, Lambert B
Abstract excerpt
Recently, much interest has been focused on instability of microsatellite DNA sequences such as di- and tri-nucleotide repeats in human cancers. Certain tumors show an increased frequency of mutation leading to repeat length variation at microsatellite loci, and it is thought that such instability may be a marker for the transformed phenotype. However, the spontaneous frequency by which repetitive DNA such as...
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