Spontaneous length variation in microsatellite DNA from human T-cell clones.

doi:10.1002/gcc.2870140310

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Article

Spontaneous length variation in microsatellite DNA from human T-cell clones.

Genes, chromosomes & cancer - 1 Nov 1995

Hackman P, Gabbani G, Osterholm A M, Hellgren D, Lambert B

Abstract excerpt

Recently, much interest has been focused on instability of microsatellite DNA sequences such as di- and tri-nucleotide repeats in human cancers. Certain tumors show an increased frequency of mutation leading to repeat length variation at microsatellite loci, and it is thought that such instabilit...

Topics

Cell Transformation, Neoplastic
Clone Cells
Colorectal Neoplasms, Hereditary Nonpolyposis
DNA, Satellite
Dinucleotide Repeats
Humans
Lung Neoplasms
Male
Minisatellite Repeats
Mutation
Reference Values
T-Lymphocytes

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