Article
A Coregulatory Role for the TRAP-Mediator Complex in Androgen Receptor-mediated Gene Expression
1 Nov 2002
Abstract excerpt
The human thyroid hormone receptor-associated protein (TRAP)-Mediator complex was originally identified as a large multimeric complex that copurifies with the thyroid hormone receptor (TR) from HeLa cells and markedly enhances TR-mediated transcription in vitro. More recent studies have implicated TRAP-Mediator as a coactivator for a broad range of nuclear hormone receptors as well as other classes of...
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