Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TRAP/SMCC/Mediator complex and thyroid hormone receptor function.

Trends in endocrinology and metabolism: TEM - 1 Apr 2001

Ito M, Roeder R G

Abstract excerpt

The TRAP/SMCC/Mediator complex is a mammalian transcriptional regulatory complex that contains over 25 polypeptides and is, in part, phylogenetically conserved. It was originally isolated as a thyroid hormone receptor (TR)-associated protein (TRAP) complex that mediates TR-activated transcription from DNA templates in conjunction with the general transcription machinery, and probably acts in vivo after the action...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Embryo, Mammalian
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fungal Proteins

Share to Hypothyroidism

Share to Mediator Complex

Share to Receptors, Thyroid Hormone

Share to Trans-Activators

Source

Identifiers

PMID: 11306338
DOI: 10.1016/s1043-2760(00)00355-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TRAP/SMCC/Mediator complex and thyroid hormone receptor function.PMID 11306338Read ↗

Activation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation.Semantic proximity Read ↗

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.Semantic proximity Read ↗

A Coregulatory Role for the TRAP-Mediator Complex in Androgen Receptor-mediated Gene ExpressionSemantic proximity Read ↗

The Mediator Complex: Progress over the Past DecadeSemantic proximity Read ↗

E3 Ubiquitin Ligase TRIP12: Regulation, Structure, and Physiopathological Functions.Semantic proximity Read ↗

A Coregulatory Role for the Mediator Complex in Prostate Cancer Cell Proliferation and Gene ExpressionSemantic proximity Read ↗

Mouse gene trap approach: identification of novel genes and characterization of their biological functions.Semantic proximity Read ↗

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.Semantic proximity Read ↗

The Function of Steroid Receptor Coactivator-1 in Normal Tissues and CancerSemantic proximity Read ↗

The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis.Semantic proximity Read ↗

Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.Semantic proximity Read ↗

Deciphering direct and indirect influence of thyroid hormone with mouse genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.