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Article

A Coregulatory Role for the Mediator Complex in Prostate Cancer Cell Proliferation and Gene Expression

1 May 2007

Abstract excerpt

Androgen receptor (AR) signaling pathways are important for the survival and proliferation of prostate cancer cells. Because AR activity is facilitated by distinct coregulatory factors and complexes, it is conceivable that some of these proteins might also play a role in promoting prostate oncogenesis. The multisubunit Mediator complex is an important coactivator for a broad range of regulatory transcriptional...

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PMID: 17483314
DOI: 10.1158/0008-5472.can-06-3039

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