Article
Identification and Characterization of ART-27, a Novel Coactivator for the Androgen Receptor N Terminus
1 Feb 2002
Abstract excerpt
The androgen receptor (AR) is a ligand-regulated transcription factor that stimulates cell growth and differentiation in androgen-responsive tissues. The AR N terminus contains two activation functions (AF-1a and AF-1b) that are necessary for maximal transcriptional enhancement by the receptor; however, the mechanisms and components regulating AR transcriptional activation are not fully understood. We sought to...
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