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Article

Cloning and Characterization of Androgen Receptor Coactivator, ARA55, in Human Prostate

1 Mar 1999

Abstract excerpt

Androgen receptor (AR) is a hormone-activated transcriptional factor that can bind to androgen response elements and that regulates the transcription of target genes via a mechanism that presumably involves cofactors. We report here the cloning of a novel AR coactivator ARA55 using a yeast two-hybrid system. ARA55 consists of 444 amino acids with the predicted molecular mass of 55 kDa and its sequence shows very...

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Share to Estrogen and related hormone effects
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PMID: 10075738
DOI: 10.1074/jbc.274.12.8316

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